Abstract
In the field of developmental biology, the understanding of embryogenesis is driven by ever-advancing techniques of studying embryos’ structures and behaviors. Yolk sacs are critical to an embryo’s survival and its function in producing a mature organism from a simple zygote. A hallmark of embryonic yolk sacs is their production of primitive hematopoietic stem cells (HSCs). Recent research has explored the mechanisms by which these HSCs develop and migrate, as well as the mechanisms by which they differentiate into various cell types. This more thorough understanding of HSCs is the basis for the development of embryo models, peri-gastruloids, from stem cells. Such models are accessible and closely resemble natural embryogenesis, making way for continued advancements in scientists’ ability to understand and develop therapies for early developmental diseases.
Recommended Citation
Shive, Lucy
(2026)
"Emergence, Differentiation, and Modeling of Hematopoietic Stem Cells in Developing Embryos,"
Caroliniana Undergraduate Research Journal: Vol. 1:
Iss.
1, Article 4.
Available at:
https://scholarcommons.sc.edu/usc-curj/vol1/iss1/4