https://doi.org/10.1093/bioinformatics/btab436

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Document Type

Article

Abstract

MOTIVATION: Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be time consuming to tackle through manual assignment and challenging for automated approaches. RESULTS: Native Mass Spectrometry Visual Analyser (NaViA) is a web-based tool to augment the manual process of peak assignment. In addition to matching masses to the stoichiometry of its component subunits it allows raw data processing, assignment and annotation and permits mass spectra to be shared with their respective interpretation. AVAILABILITY: NaViA is open-source and can be accessed online under https://navia.ms. The source code and documentation can be accessed at https://github.com/d-que/navia, under the BSD 2-Clause license. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Digital Object Identifier (DOI)

https://doi.org/10.1093/bioinformatics/btab436

APA Citation

Quetschlich, D., Esser, T., Newport, T., Fiorentino, F., Shutin, D., & Chen, S. et al. (2021). NaViA: a program for the visual analysis of complex mass spectra. Bioinformatics, 37(24), 4876-4878. https://doi.org/10.1093/bioinformatics/btab436

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