Document Type
Article
Abstract
Infammation is considered a key mechanism leading to obesity. Dietary patterns and certain food items infuence infammation. Few studies have investigated the contribution of major dietary patterns to biological measures of infammation. Therefore, the present study aimed to examine the associations of diferent dietary patterns with dietary infammatory index (DII), systemic infammation, and insulin resistance (IR) in the apparently healthy obese. In this cross-sectional study, 151 abdominally obese subjects were recruited from the Northwest of Iran. Dietary intake, demographic data, anthropometric indices, and physical activity (PA) was assessed. DII scores were calculated based on a validated 168-item food frequency questionnaire (FFQ). Three dietary patterns were identifed, using principal component analysis. Basal blood samples were collected to determine biochemical parameters. Linear regression test with adjusted beta estimates was applied for data analysis. Three dietary patterns were extracted as Healthy, Western, and Traditional. Body mass index (BMI) (p< 0.01) and fat mass (p< 0.001) were directly associated with the Western dietary pattern. Conversely, serum lipopolysaccharide-binding protein (LBP) (b= − 0.1, p< 0.04) was negatively associated with Healthy dietary pattern, after controlling for confounders. The Traditional pattern was found to be inversely related to DII (b= − 0.3, p< 0.001). The association was also reveresed between Traditional pattern and IR (Odds Ratio: 0.3 (95% Confdence Interval 0.1–0.9)). The results suggested that the Western dietary pattern was related to higher BMI and fat mass. In addition, the Healthy pattern was associated with decreased levels of LBP. Adherence to the Traditional dietary pattern was inversely related to DII as well as IR.
Digital Object Identifier (DOI)
Publication Info
Published in Scientific Reports, Volume 11, Issue 7515, 2021.
Rights
© The Author(s) 2021 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
APA Citation
Saghafi-Asl, M., Mirmajidi, S., Asghari Jafarabadi, M., Vahid, F., Shivappa, N., Hébert, J. R., & Ebrahimzadeh Attari, V. (2021). The association of dietary patterns with dietary inflammatory index, systemic inflammation, and insulin resistance, in apparently healthy individuals with obesity. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-86993-7