Abstract
Human Papillomavirus (HPV) is, according to the CDC, the most common sexually transmitted infection (STI) with many infections developing in a person's late teens or early 20’s. HPV is a nonenveloped, relatively small, icosahedral DNA virus that infects squamous epithelial cells. This infection can happen in genital, anal, and oral cavities. 90% of these infections will self-clear in two years according to the CDC. Of the 10% of infections that do not clear in two years, they could develop into carcinomas later in life. The goal of this developmental research is to create a polymerase chain reaction (PCR) that can detect HPV genomic material from a human oral self-sample. The methodology of the self-sample was determined through several trials using three anonymous volunteers.
Recommended Citation
Bishop, Emily; Smith, Owen; and Richardson, Paul E.
(2024)
"Development of a Simple and Accurate Polymerase Chain Reaction Screen for Human Papillomavirus in College Students,"
Journal of the South Carolina Academy of Science: Vol. 22:
Iss.
1, Article 4.
Available at:
https://scholarcommons.sc.edu/jscas/vol22/iss1/4