Document Type


Subject Area(s)

Materials Chemistry


A thin film sensor for the detection of volatile organic compounds (VOC) was fabricated by deposition of oligo-aniline grafted tobacco mosaic virus (TMV) onto a glass substrate. The oligo-aniline motifs were conjugated onto the TMV surface by a traditional diazonium coupling reaction to tyrosine residues followed by Cu(I) catalyzed alkyne-azide cycloaddition (CuAAC) reaction. The modified TMV was easily fabricated into a thin film by directly drop coating onto a glass substrate. Upon integration of the glass substrate into a prototypical device, the virus-based thin film exhibited good sensitivity and selectivity toward ethanol and methanol vapour.

Digital Object Identifier (DOI)

APA Citation

Bruckman, M., Liu, J., Koley, G., Li, Y., Benicewicz, B., Niu, Z., & Wang, Q. (2010). Tobacco Mosaic Virus Based Thin Film Sensor for Detection of Volatile Organic Compounds. Journal of Materials Chemistry, 20(27), 5715–5719.


© Journal of Materials Chemistry 2010, Royal Society of Chemistry.