Neovascular Age-Related Macular Degeneration Is Associated with Cataract Surgery
Document Type
Article
Abstract
PURPOSE: This retrospective cohort study examines the association between cataract surgery and neovascular age-related macular degeneration (AMD) during 5-year follow-up using population-based claims data. METHODS: We analysed data sourced from the Taiwan Longitudinal Health Insurance Database 2005. The study included 3465 patients who had undergone cataract operations and did not have a diagnosis of AMD before or on the surgery date (study group), and 10 395 age- and sex-matched comparison patients selected randomly from the remaining patients without an AMD diagnosis before the index date. We tracked the claims of each patient for a 5-year period to identify patients with a subsequent diagnosis of neovascular AMD. RESULTS: The incidence rate of neovascular AMD was 0.88 (95% confidence interval (CI): 0.66-1.14) per 1000 person-years among all sampled patients, 1.60 (95% CI: 1.04-2.36) among the cataract surgery patients and 0.64 (95% CI: 0.43-0.91) among comparison patients (p < 0.001). Stratified Cox proportional analysis showed that relative to the comparison cohort, the adjusted hazard ratio for neovascular AMD during 5-year follow-up was 2.68 (95% CI: 1.55-4.66) for patients who had undergone cataract operation. We censored those who died during follow-up period and adjusted for patients' monthly income, geographical location, urbanization level, diabetes, hypertension, cardiovascular disease and hyperlipidaemia. CONCLUSION: This study demonstrated epidemiological evidence of a link between cataract surgery and neovascular AMD during a 5-year follow-up period.
Digital Object Identifier (DOI)
Publication Info
Published in ACTA Ophthalmologica, Volume 96, Issue 2, 2018, pages e213-e217.
APA Citation
Ho, J.-D., Xirasagar, S., Kao, L.-T., & Lin, H.-C. (2017). Neovascular age-related macular degeneration is associated with cataract surgery. Acta Ophthalmologica, 96(2), e213–e217. https://doi.org/10.1111/aos.13511
Rights
© 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd