Document Type
Article
Abstract
Significance: Near-infrared spectroscopy (NIRS) is a noninvasive technique that uses scalp-placed sensors to measure cerebral hemoglobin concentration. Commercial NIRS instruments do not allow for whole-head coverage and do not intrinsically indicate which brain areas generate the NIRS signal. Hence, the challenge is to design source–detector channel arrangement that maximizes sensitivity to a given brain region of interest (ROI). Existing methods for optimizing channel placement design have been developed using adult head models. Thus, they have limited utility for developmental research.
Aim: We aim to build an application from an existing toolbox (fOLD) that guides NIRS channel configuration based on age group, stereotaxic atlas, and ROI (devfOLD).
Approach: The devfOLD provides NIRS channel-to-ROI specificity computed using photon propagation simulation with realistic head models from infant, child, and adult age groups.
Results: Cortical locations and user-specified specificity cut-off values influence the between-age consistency and differences in the ROI-to-channel correspondence among the example infant and adult age groups.
Conclusions: The study highlights the importance of incorporating age-specific head models for optimizing NIRS channel configurations. The devfOLD toolbox is publicly shared and compatible with multiple operating systems.
Digital Object Identifier (DOI)
Publication Info
Published in Neurophoton, Volume 8, Issue 4, 2021, pages 045003-.
Rights
© The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.