Abstract
Recent literature reports examples of electrochemical biosensor systems that have been developed based upon on the encapsulation of enzymes and metal nanoparticles into a xerogel. These systems have been utilized for the detection of biologically important compounds, such as glucose. These reports on these systems have found acceptable detection limits and linear ranges. At the same time, Prussian blue modified electrodes have been shown to have better operating parameters than metal electrodes for the detection of hydrogen peroxide. In this work, a biosensor system is described that incorporates the encapsulation of glucose oxidize within a xerogel combined with electrochemical detection based on Prussian blue modified electrodes. Two systems which differ in the placement of the Prussian blue material are discussed. The first is an electrochemical system where the Prussian blue is on the electrode surface under the xerogel was found to have linear response to glucose concentrations between 1.0 X 10-5 M and 1.0 X 10-3 M. The second is where the Prussian blue is deposited within the xerogel was found to have a linear response between 1.0X10-5 M to 1.0X10-3 M. Both of these electrochemical systems show promise for the detection of glucose at biologically relevant concentrations.
Recommended Citation
Baker, Daniel; Davis, Sarah; and Budner, Drew
(2024)
"Electrochemical Detection of Glucose Using a Prussian Blue Modified Electrodes Combined with Glucose Encapsulated within a Xerogel,"
Journal of the South Carolina Academy of Science: Vol. 22:
Iss.
1, Article 3.
Available at:
https://scholarcommons.sc.edu/jscas/vol22/iss1/3