Abstract
Vitamin A has an essential role in vision in that it forms the photosensitive pigments that absorb light and initiate the visual process. However, vitamin A and its analogues also have critical roles in maintaining the structural integrity of the retina. Disruption of the metabolism of vitamin A results in several blinding diseases. This review focuses on our recent studies on the role of a protein critical to the processing of vitamin A, RPE65. The absence or dysfunction of this protein causes the childhood blinding disease Leber congenital amaurosis.
Recommended Citation
Crouch, Rosalie K.; Kono, Masahiro; and Tang, Peter H.
(2014)
"Role of Vitamin A in Retinal Diseases,"
Journal of the South Carolina Academy of Science: Vol. 12:
Iss.
1, Article 3.
Available at:
https://scholarcommons.sc.edu/jscas/vol12/iss1/3