Crosslinking by Advanced Glycation End Products Increases the Stiffness of the Collagen Network in Human Articular Cartilage: A Possible Mechanism Through Which Age Is a Risk Factor for Osteoarthritis

Author(s)

Nicole Verzijl
Jeroen DeGroot
Chaya Ben Zacken
Orit Braun-Benjamin
Alice Maroudas
Ruud A. Bank
Joe Mizrahi
Casper G. Schalkwijk
Suzanne R. Thorpe
John W. Baynes, University of South Carolina - ColumbiaFollow
Johannes W.J. Bijlsma
Floris P.J.G. Lafeber
Johan M. TeKoppele

Document Type

Article

Subject Area(s)

Medicine and Health Sciences, Rheumatology, Medical Biochemistry

Publication Info

Published in Arthritis & Rheumatology, Volume 46, Issue 17, 2002, pages 114-123.

Rights

Verzijl N., DeGroot J., Zaken C. B., Braun-Benjamin O., Maroudas A., Bank R. A., Mizrahi J., Schalkwijk C. G., Thorpe S. R., Baynes J. W., Bijlsma J. W. J., Lafeber F. P. J. G. and TeKoppele J. M. (2002). Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: A possible mechanism through which age is a risk factor for osteoarthritis. Arthritis & Rheumatism. 46(1): 114–123.

©Arthritis & Rheumatism, 2002, The American College of Rheumatology

http://dx.doi.org/10.1002/1529-0131(200201)46:1<114::AID-ART10025>3.0.CO;2-P