Date of Award

Summer 2023

Document Type

Open Access Dissertation


Chemistry and Biochemistry

First Advisor

Ken D. Shimizu


The main focus of this dissertation is on the quantification of non-covalent interactions using molecular rotors and balances. While molecular rotors were used to measure kinetic effects of weak non-covalent interactions, molecular balances were used to measure their thermodynamic effects. Chapters 1 and 2 focus on the use of molecular rotors in measuring and studying the kinetic effects of the hydrogen bonding interaction on the bond rotation transition states. Chapters 3 and 4 focus on the quantification of lone pair – lone pair and sp2-CH/π interactions respectively, using molecular balances. These studies were carried out in the ground state.


© 2023, Daniel Onyekachi Madukwe

Included in

Chemistry Commons