Date of Award

Spring 2022

Document Type

Open Access Dissertation


Chemistry and Biochemistry

First Advisor

Dmitry V. Peryshkov


In the past few decades, main group-based catalysts have attracted increasing attention as an alternative approach to overcome the most prevailing issues of transition metal catalysts such as high cost, toxicity, and low abundance. Among these main groupbased catalysts, Phosphine based compounds have shown a variety of bond activations due to the strong nucleophilicity from their congener species. To the contrary, unique electron deficient boron-based clusters have the tendency to accept two electrons reversibly due to their electron deficiency. In this study, we have synchronized the electron donor ability of the phosphine with the electron acceptor ability of the ortho-carborane to construct a new carboranyl phosphine cluster. The unusual steric and electronic properties of this cluster have demonstrated strong bond activation analogous to transition metal-based bond activation such as oxidative addition and reductive elimination. Herein, metal free activation of small molecules by the carboranyl phosphine ligand and its applications will be introduced.


© 2022, Gayathri B. Gange

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