Computer Science and Engineering, Chemistry
At pH > 6 added filamentous bacteriophage fd is compatible with many of the detergents used to solubilize membrane proteins for solution NMR studies of membrane proteins and, therefore, serves as an alignment media. In combination with strained polyacrylamide gel alignment, Dipolar Waves can be used to directly assess the secondary structure and a λ-map extracts the order tensors for de novo structure calculation of membrane proteins without distance restraints.
Published in Journal of the American Chemical Society, Volume 131, Issue 40, 2009, pages 14140-14141.
© 2009 by the American Chemical Society