Objective: To examine prospectively the association between muscular strength and mortality from all causes, cardiovascular disease, and cancer in men.
Design: Prospective cohort study.
Setting: Aerobics center longitudinal study.
Participants: 8762 men aged 20-80.
Main outcome measures: All cause mortality up to 31 December 2003; muscular strength, quantified by combining one repetition maximal measures for leg and bench presses and further categorised as age specific thirds of the combined strength variable; and cardiorespiratory fitness assessed by a maximal exercise test on a treadmill.
Results: During an average follow-up of 18.9 years, 503 deaths occurred (145 cardiovascular disease, 199 cancer). Age adjusted death rates per 10,000 person years across incremental thirds of muscular strength were 38.9, 25.9, and 26.6 for all causes; 12.1, 7.6, and 6.6 for cardiovascular disease; and 6.1, 4.9, and 4.2 for cancer (all P
Conclusion: Muscular strength is inversely and independently associated with death from all causes and cancer in men, even after adjusting for cardiorespiratory fitness and other potential confounders.
Published in British Medical Journal, Volume 337, Issue a439, 2008, pages 92-95.
Ruiz, J. R., Sui, X., Lobelo, F., Morrow, Jr., J. R., Jackson, A. W., Sjörström, M., & Blair, S. N. (2008). Association between muscular strength and mortality in men: Prospective cohort study. British Medical Journal, 337(a439), 92-95.
© British Medical Journal, 2008, BMJ Publishing Group