Date of Award


Document Type

Open Access Thesis


Exercise Science


Norman J. Arnold School of Public Health

First Advisor

Xuewen Wang


Introduction: As obesity continues to be a major public health concern, exercise is continually at the forefront of combating this epidemic. This thesis aims to examine how two different doses of exercise may affect the “hunger hormone”, ghrelin; in postmenopausal, non-obese women. Methods: 54 non-obese postmenopausal women were randomly assigned to either a higher dose (energy expenditure = 14 kilocalories/per kilogram of body weight/per week) or lower dose (energy expenditure = 8 kcal/kg/week) aerobic exercise training group for 16 weeks. Fasting blood samples were taken at baseline and at post intervention for analysis of ghrelin via multiplex immunoassay. Results: Only the higher dose exercise group had a decrease in ghrelin concentration following 16 weeks of moderate intensity aerobic exercise. Conclusion: Higher dose aerobic exercise training significantly decreased fasting ghrelin concentration and increased VO2 in non-obese postmenopausal women while the lower-dose chronic exercise training did not.