Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types, Maksim Erokhin, Olga Chetverina, Balázs Győrffy, Victor V. Tatarskiy, Vladic Mogila, Alexander A. Shtil, Igor Roninson, Jerome Moreaux, Pavel Georgiev, Giacomo Cavalli, Darya Chetverina
Faculty Publications

Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition, Mengqian Chen, Jing Li, Jiaxin Liang, Zanshé S. Thompson, Katie Kathrein, Eugenia Broude, Igor Roninson
Faculty Publications

Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay, Jng Li, Donald C. Porter, Eugenia Broude, Igor Roninson, Mengqian Chen
Faculty Publications

Identifying Cancers for CDK8/19 Inhibitor Therapy, Igor Roninson, Balázs Győrffy, Zachary T. Mack, Alexander A. Shtil, Michael S. Shtutman, Mengqian Chen, Eugenia Broude
Faculty Publications

Role of Transcription-Regulating Kinase CDK8 in Colon Cancer Metastasis, Jiaxin Liang, Mengqian Chen, Eugenia Broude, Igor Roninson
Faculty Publications

Inhibition of CDK8 Mediator Kinase Suppresses Estrogen Dependent Transcription and the Growth of Estrogen Receptor Positive Breast Cancer, Martina S. McDermott, Alexander A. Chumanevich, Chang-Uk Lim, Jiaxin Liang, Mengqian Chen, Serena Altilia, David Oliver, James M. Rae, Michael Shtutman, Hippokratis Kiaris, Balázs Győrffy, Igor Roninson, Eugenia Broude
Faculty Publications

Identification of Novel Genes That Regulate Androgen Receptor Signaling and Growth of Androgen-Deprived Prostate Cancer Cells, Elina Levina, Hao Ji, Mengqiang Chen, Mirza Baig, David Oliver, Patrice Ohouo, Chang-Uk Lim, Garry Schools, Steven Carmack, Ye Ding, Eugenia Broude, Igor Roninson, Ralph Buttyan, Michael Shtutman
Faculty Publications

Reactive Oxygen Species and Mitochondrial Sensitivity to Oxidative Stress Determine Induction of Cancer Cell Death by p21, Ionica Masgras, Samantha Carrera, Petra J. de Verdier, Paul Brennan, Aneela Majid, Wan Makhtar, Eugene Tulchinsky, George D. Jones, Igor Roninson, Salvador Macip
Faculty Publications

TP53 Codon 72 Polymorphism Affects Accumulation of mtDNA Damage in Human Cells, Serena Altilia, Aurelia Santoro, Davide Malagoli, Catia Lanzarini, Josué Adolfo Ballesteros Álvarez, Gianluca Galazzo, Donald Carl Porter, Paolina Crocco, Giuseppina Rose, Giuseppe Passarino, Igor Roninson, Claudio Franceschi, Stefano Salvioli
Faculty Publications

Identification of Single Nucleotide Polymorphisms in the P21 (CDKN1A) Gene and Correlations With Longevity in the Italian Population, Silvia Gravina, Francesco Lescai, Gregory Hurteau, Graham J. Brock, Anna Saramaki, Stefano Salvioli, Claudio Franceschi, Igor Roninson
Faculty Publications

A Structural Interpretation of the Effect of GC-Content on Efficiency of RNA Interference, Chi Yu Chan, C Steven Carmack, Dang D. Long, Anil Maliyekkel, Yu Shao, Igor Roninson, Ye Ding
Faculty Publications

Repression of the Sumo-Specific Protease SENP1 Induces P53-Dependent Premature Senescence in Normal Human Fibroblasts, Kristin E. Yates, Gregory A. Korbel, Michael Shtutman, Igor Roninson, Daniel DiMaio
Faculty Publications