Prevalence, Disparities, and Health Outcomes in Patients With Alzheimer’s Disease, Dementia, and Mild Cognitive Impairment, Xiaomo Xiong
Theses and Dissertations

PD-L1 Nano-Eraser: A Novel Intracellular PD-L1 Degradation Approach and Its Application in Cancer and Alzheimer’s Disease Therapy, Mingming Wang
Theses and Dissertations

CDK8 AND CDK19 Mediator Kinases as Novel Targets in Advanced Prostate Cancer, Jing Li
Theses and Dissertations

The Mechanism of PDA-PEG/Copper Selectively Killing Cancer Cells and Its Application in Treating Triple-Negative Breast Cancer and Advanced Ovarian Cancer, Xiangxiang Hu
Theses and Dissertations

Drug Repurposing: New Mechanisms and Applications of Existing Compounds, Biyun Celia Cui
Theses and Dissertations

Targeting of Mediator Kinases for Cancer Therapy and Resistance Prevention, Zachary Thomas Mack
Theses and Dissertations

Impacts of FDA Approval and Medicare Restriction on Antiamyloid Therapies for Alzheimer’s Disease: Patient Outcomes, Healthcare Costs, and Drug Development, Rouen Brockmann, Joanna Nixon, Bryan L. Love Pharm D., Ismaeel Yunusa Ph. D.
Faculty Publications

Intensive Care Unit Mortality and Length of Stay Among Critically Ill Patients With Sepsis Treated With Corticosteroids: A Retrospective Cohort Study, Eric E. Chinaeke, Ismaeel Yunusa Ph.D., Bryan L. Love Pharm. D., Joseph Magagnoli, Claiborne E. Reeder
Faculty Publications

The Global Fatty Liver Disease-Sustainable Development Goal Country Score for 195 Countries and Territories, Jeffrey V. Lazarus, Hannah Han, Henry E. Mark, Saleh A. Schattenberg, Jörn M. J., Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Racial and Ethnic Disparities in Alcohol-Attributed Deaths in the United States, 1999–2020, Ibraheem M. Karaye, Nasim Maleki, Ismaeel Yunusa Ph.D.
Faculty Publications

UP-02 Pharmacological and Non-pharmacological Interventions for the Treatment of Neonatal Abstinence Syndrome, Taylor Meetze, Reagan Bradley, Peyton Smith, Emily Sisk, Ryan Crawford
SC Upstate Research Symposium

GP-03 Synthesis and Antimicrobial Activity of Novel Puromycin Analogs, Adrianna L. Cody, Giuseppe Gumina
SC Upstate Research Symposium

Comparative-Effectiveness of Oral Beta-Lactams and Fluoroquinolones for Stepdown Therapy in Patients With Enterobacterales Bloodstream Infections: A Retrospective Cohort Study, Lauren Bjork Ph.D., Teri Hopkins Ph.D., Linda Yang Ph.D., Chengwen Teng Pharm.D., Ph.D., Xavier Jones BS, Jose Cadena, Elizabeth Walter, Christopher R. Frei Pham.D., MS
Faculty Publications

Global Investments in Pandemic Preparedness and COVID-19: Development Assistance and Domestic Spending on Health Between 1990 and 2026, Angela E. Micah, Kayleigh Bhangdia, Ian E. Cogswell, Dylan Lasher, Brendan Lidral-Porter, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

COVID-19 Vaccination in Africa: A Case of Unsatisfied Expectation and Ill-Preparedness, Osmond C. Ekwebelem, Phemelo Tamasiga, Abullhai Tunde Abonde, Ismaeel Yunusa Ph. D., Uju Nwauzoma, Helen Onyeaka
Faculty Publications

Pre-existing Diabetes Mellitus, Hypertension and KidneyDisease as Risk Factors of Pre-eclampsia: A Disease of Theories and Its Association With Genetic Polymorphism, Abdullah Salah Alanazi, Francis Victor, Kanwal Rehman, Yusra Habib Khan, Ismaeel Yunusa Ph.D., Abdulaziz Alzarea, Muhammad Sajid Hamid Akash, Tauqeer Hussain Mallhi
Faculty Publications

Epidemiology, Outcomes and Tolerability of Protracted Treatment of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States, Yuwei Vivian Tsai, Caroline Derrick, Ismaeel Yunusa Ph. D., Sharon Weissman, Majdi N. Al-Hasan, Julie Ann Justo Pharm. D., P. Brandon Bookstaver Pharm. D.
Faculty Publications

Epidemiology, Outcomes and Tolerability of Protracted Treatment of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States, Yuwei Vivian Tsai, Carolina Derrick, Ismaeel Yunusa Ph.D., Sharon Weissman, Majdi N. Al-Hasan, Julie Ann Justo Pharm.D., P. Brandon Bookstaver Pharm.D.
Faculty Publications

Genomic Analysis Workflows to Identify Mutational Signatures and Structural Variations in OVCAR8 Cells and Rad51d-deficient Mouse Embryonic Fibroblasts, Manli Yang
Theses and Dissertations

Peromyscus Maniculatus Bairdii and Peromyscus Maniculatus Sonoriensis Polymorphisms, Matthew Dixon Lucius
Theses and Dissertations

Changes in the Regulation of the Unfolded Protein Response During Aging in Peromyscus, Elham Soltanmohammadi
Theses and Dissertations

Development of Peptidomimetic Inhibitors Targeting the Polo Box Domain of PLK1 as Potential Cancer Therapeutics, Jessy Mariam Stafford
Theses and Dissertations

Ribosomal RACK1 Regulates the Dendritic Arborization by Repressing FMRP Activity, Nicla Romano, Bruna Di Giacomo, Veronica Nobile, Antonella Borreca, Daniela Willems, Francesca Tilesi, Elisabetta Catalani, Manasi Agrawal, Kristy Welshhans, Sara Ricciardi, Davide Cervia, Marcello Ceci
Faculty Publications

The Risk and Clinical Implications of Antibiotic-Associated Acute Kidney Injury: A Review of the Clinical Data for Agents with Signals from the Food and Drug Administration’s Adverse Event Reporting System (FAERS) Database, Kalin M. Clifford, Ashley R. Selby, Kelly R. Reveles, Chengwen Teng, Ronald G. Hall II, Jamie McCarrell, Carlos A. Alvarez
Faculty Publications

Assessing Performance of the Healthcare Access and Quality Index, Overall and by Select Age Groups, for 204 Countries and Territories, 1990–2019: A Systematic Analysis From the Global Burden of Disease Study 2019, Annie Haakenstad, Jamal Akeem Yearwood, Nancy Fullman, Corinne Bintz, Kelly Bienhoff, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Direct Material Property Determination: One‐Dimensional Formulation Utilising Full‐Field Deformation Measurements, Sreehair Rajan-Kattil, Michael A. Sutton, Subramani Sockalingam, Frank Thomas, Tusit Weerasooriya, Stephen Alexander
Faculty Publications

The Global, Regional, and National Burden of Benign Prostatic Hyperplasia in 204 Countries and Territories From 2000 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Atalel Fentahun, Hannah Han, Behzad Abbasi, Mohsen Abbasi-Kangevari, Muktar Beshir Ahmed, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Adolescent Transport and Unintentional Injuries: A Systematic Analysis Using the Global Burden of Disease Study 2019, Amy E. Peden, Patricia Cullen, Kate Louise Francis, Holger Moeller, Margaret M. Peden, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

From Start to Finish: Examining Factors Associated With Higher Likelihood of Publication Among Abstracts Presented at an International Infectious Diseases Scientific Meeting, Asia J. Johnson, Christopher M. Bland, Chengwen Teng, Lily Zheng, J Colin Hungerpiller, Morgan Easterling, Sarah Arnold, Madeline Dean, Carrington Royals, P. Brandon Bookstaver
Faculty Publications

The Global Burden of Cancer Attributable to Risk Factors, 2010-19: A Systematic Analysis for the Global Burden of Disease Study 2019, Khanh Bao Tran, Justin J. Lang, Kelly Compton, Rixing Xu, Alistair R. Acheson, Hannah Jacqueline Henrikson, Jonathan M. Kocarnik, Louise Penberthy, Amirali Aali, Qamar Abbas, Behzad Abbasi, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Michael Abdelmasseh, Sherief Abd-Elsalam, Ahmed Abdelwahab Abdelwahab, Gholamreza Abdoli, Hanan Abdulkadir Abdulkadir, Aidin Abedi, Ismaeel Yunusa, Et. Al.
Faculty Publications

Retrospective Cohort Evaluating the Comparative Effectiveness of Ceftaroline and Daptomycin as First-Line Therapies for Inpatient Treatment of Diabetic Foot Infection in the United States Veterans Health Care System, Alyssa C. Eaves, Chengwen Teng Pharm.D., Ph.D., Kirk E. Evoy, Christopher R. Frei
Faculty Publications

Mediator Kinase Inhibitors for Breast Cancer Therapy, Xiaokai Ding
Theses and Dissertations

Discovery and Mechanistic Study of Novel PBD-Targeted Inhibitors of PLK1 for Prostate Cancer Treatment, Danda Pani Chapagai
Theses and Dissertations

Do We Trust the Government? Attributes of COVID-19 Vaccine Hesitancy and Acceptance in Nigeria, Osmond C. Ekwebelem, Helen Onyeaka, Ismaeel Yunusa Ph. D., Taghi Miri, Yahwedalu M. Onwuneme, Ayeni T. Eunice, Amara Anyogu, Bright Obi, Ngwogu Ada Carol
Faculty Publications

Delirium Associations With Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS), Chengwen Teng, Christopher R. Frei
Faculty Publications

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 a Systematic Analysis for the Global Burden of Disease Study 2019, Ismaeel Yunusa Ph.D., Jonathan M. Kocarnik, Kelly Compton, Frances E. Dean, Weijia Fu, Brian L. Gaw, Et. Al.
Faculty Publications

Diabetes Mortality and Trends Before 25 Years of Age: An Analysis of the Global Burden of Disease Study 2019, Ewerton Cousin, Bruce B. Duncan, Carolina Stein, Kanyin Liane Ong, Theo Vos, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Global, Regional, and National Sex Differences in the Global Burden of Tuberculosis by HIV Status, 1990-2019: Results From the Global Burden of Disease Study 2019, Jorge R. Ledesma, Jianing Ma, Avina Vongpradith, Emilie R. Maddison, Amanda Novotney, Ismaeel Yunusa
Faculty Publications

Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors, Ismaeel Yunusa, Joshua J. Gagne, Kazuki Yoshida, Katsiaryna Bykov
Faculty Publications

Estimation of the Global Prevalence of Dementia in 2019 and Forecasted Prevalence in 2050: An Analysis for the Global Burden of Disease Study 2019, Emma Nichols, Jaimie D. Steinmetz, Stein Emil Vollset, Kai Fukutaki, Julian Chalek, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

In Vitro Activity of Non-antibiotic Drugs Against Staphylococcus Aureus Clinical Strains, Natalie K. Boyd, Grace C. Lee, Chengwen Teng Pharm.D., Ph.D., Christopher R. Frei
Faculty Publications

The Global Burden of Adolescent and Young Adult Cancer in 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Elysia M. Alvarez, Lisa M. Force, Rixing Xu, Kelly Compton, Dan Lu, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Trends in Insulin Prescribing for Patients With Diabetes During the COVID-19 Pandemic in the US, Ismaeel Yunusa Ph.D., Bryan L. Love Pharm D., Chao Cai, Tessa Hastings, Claiborne E. Reeder, Elizabeh W. Blake, Cynthia Phillips
Faculty Publications

Estimated Cost-Effectiveness of Atezolizumab Plus Cobimetinib and Vemurafenib for Treatment of BRAF V600 Variation Metastatic Melanoma, Chao Cai, Ismaeel Yunusa Ph.D., Ahmad Tarhini
Faculty Publications

Global, Regional, and National Burden of Stroke and Its Risk Factors, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Ismaeel Yunusa, Valery L. Feigin, Benjamin A. Stark, Caterine Owens Johnson, Gregory A. Roth, Catherine Bisignano, Et Al.
Faculty Publications

Sex Differences and Neuroimmune Effects of Microglial Response in the Mesolimbic Reward Pathway in Nicotine Substance Use Disorder, Erin Leigh Anderson
Theses and Dissertations

Age-Dependent Increase in Tyrosine Level Depletes Tyrosyl-tRNA Synthetase and Causes Neuronal Oxidative DNA Damage in Alzheimer’s Disease, Megha Jhanji
Theses and Dissertations

The Development of Novel CDK8 and CDK19 Inhibitors and Degraders as Potential Anti-cancer Agents, Li Zhang
Theses and Dissertations

Variations in ER Stress and Unfolded Protein Response Predict Disease Susceptibility, Youwen Zhang
Theses and Dissertations

Global, Regional, and National Burden of Stroke and Its Risk Factors, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, Valery L. Feigin, Benjamin A. Stark, Catherine Owens Johnson, Gregory A. Roth, Gdiom Gebreheat Abady, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Global, Regional, and National Sex-Specific Burden and Control of the HIV Epidemic, 1990-2019, for 204 Countries and Territories: The Global Burden of Diseases Study 2019, Deepa Jahagirdar, Magdalene K. Walters, Amanda Novotney, Edmond D. Brewer, Tahvi D. Frank, Ismaeel Yunusa Ph.D., Et. Al.
Faculty Publications

Fatal Police Violence by Race and State in the USA, 1980–2019: A Network Meta-Regression, Fablina Sharara, Eve E. Wool, Gregory J. Bertolacci, Nicole Davis Weaver, Shelley Balassyano, Ismaeel Yunusa Ph. D., Et Al.
Faculty Publications

Tracking Development Assistance for Health and for COVID-19: A Review of Development Assistance, Government, Out-Of-Pocket, and Other Private Spending on Health for 204 Countries and Territories, 1990–2050, Angela E. Micah, Ian E. Cogswell, Brandon Cunningham, Satoshi Ezoe, Anton C. Harle, Ismaeel Yunusa Ph. D.
Faculty Publications

A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in 2020, Sarah B. Green, Kayla R. Stover, Katie Barber, Jeannette L. Bouchard, Matthew L. Brown, Connor R. Deri, Bailey J. Francis, Timothy P. Gauthier, Jillian E. Hayes, Ashley H. Marx, Edoabasi U. McGee, Krutika Mediwala, Rachel J. Musgrove, Douglas Slain, Stefanie A. Stramel, Christopher M. Bland, P Brandon Bookstaver
Faculty Publications

Comparative Value of Cholinesterase Inhibitors and Memantine in Persons With Moderate-To-Severe Alzheimer’s Disease in the United States: A Cost-Effectiveness Analysis, Ismaeel Yunusa, Saud Alsahali, Amey Ranes, Tewodros Eguale
Faculty Publications

Coronary Heart Disease (CHD) In Elderly Patients: Which Drug to Choose, Ticagrelor and Clopidogrel? A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Mohammed Ahmed Akkaif, Abubakar Sha'aban, Nur Aizati Athirah Daud, Ismaeel Yunusa Ph.D., Mei Li Ng, Muhamad Ali Sk Abdul Kader, Dzul Azri Mohamed Noor, Baharudin Ibrahim
Faculty Publications

Measuring Routine Childhood Vaccination Coverage in 204 Countries and Territories, 1980–2019: A Systematic Analysis for the Global Burden of Disease Study 2020, Release 1, Natalie C. Galles, Patrick Y. Liu, Rachel L. Updike, Nancy Fullman, Jason Nguyen, Sam Rolfe, Ismaeel Yunusa, Et Al.
Faculty Publications

Knowledge Assessment of Anti-snake Venom Among Healthcare Practitioners in Northern Nigeria, Auwal A. Bala, Abubakar Jatau, Ismaeel Yunusa Ph.D., Mustapha Mohammed, Al-Kassim H. Mohammed, Abubakar M. Isa, Abubakar S. Wada, Kabiru A. Gulma, Inuwa Bello, Sani Malami
Faculty Publications

Market Segmentation and Targeted Messaging to Improve HPV Vaccine Intentions in the College Aged Population, Ashley Caitlin Godwin
Theses and Dissertations

Rabies Postexposure Prophylaxis in the United States: Opportunities to Improve Access, Coordination, and Delivery, Gavin T. Howington, Huy-Binh Nguyen, P Brandon Bookstaver, Peter Akpunonu, Joshua T. Swan
Faculty Publications

Increased Risk of Death Triggered by Domestic Violence, Hunger, Suicide, Exhausted Health System During COVID-19 Pandemic: Why, How and Solutions, Kenneth Bitrus David, Abdullahi Tunde Aborode, Damilola Quazeem Olaoye, Ndikpongkeabasi Victor Enang, Aboaba Kazeem Oriyomi, Ismaeel Yunusa
Faculty Publications

Quality Assessment of Published Systematic Reviews in High Impact Cardiology Journals: Revisiting the Evidence Pyramid, Abdelrahman Abushouk, Ismaeel Yunusa Ph.D., Abdelmagid M. Elmatboly, Shady Fayek, Omar M. Abdelfattah, Anas Saad, Isogai Toshiaki, Shashank Shekhar, Ankur Kalra, Grant W. Reed, Rishi Puri, Samir Kapadia
Faculty Publications

Spatial, Temporal, and Demographic Patterns in Prevalence of Smoking Tobacco Use and Attributable Disease Burden in 204 Countries and Territories, 1990-2019: A Systematic Analysis From the Global Burden of Disease Study 2019, Ismaeel Yunusa Ph. D., Marissa B. Reitsma, Parkes J. Kendrick, Emad Ababneh, Cristiana Abbafati, Mohsen Abbasi-Kangevari, Et. Al.
Faculty Publications

Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types, Maksim Erokhin, Olga Chetverina, Balázs Győrffy, Victor V. Tatarskiy, Vladic Mogila, Alexander A. Shtil, Igor Roninson, Jerome Moreaux, Pavel Georgiev, Giacomo Cavalli, Darya Chetverina
Faculty Publications

Brief Overview of Approaches and Challenges in New Antibiotic Development: A Focus on Drug Repurposing, Natalie K. Boyd, Chengwen Teng Pharm.D., Ph.D., Christopher R. Frei
Faculty Publications

Brief Overview of Approaches and Challenges in New Antibiotic Development: A Focus On Drug Repurposing, Natalie K. Boyd, Chengwen Teng, Christopher R. Frei
Faculty Publications

Repurposing of Antibiotics for Clinical Management of COVID-19: A Narrative Review, Abdourahamane Yacouba, Ahmed Olowo-Okere, Ismaeel Yunusa Ph.D.
Faculty Publications

Impact of Follow up Blood Cultures on Outcomes of Patients With Community-Onset Gram-Negative Bloodstream Infection, Rajiv Amipara, Hana Rac Winders, Julie Ann Justo, P. Brandon Bookstaver Pharm.D, Joseph Kohn, Majdi N. Al-Hasan
Faculty Publications

Impact of Follow up Blood Cultures on Outcomes of Patients with Community-Onset Gram-Negative Bloodstream Infection, Rajiv Amipara, Hana Rac Winders, Julie Ann Justo, P Brandon Bookstaver, Joseph Kohn, Majdi N. Al-Hasan
Faculty Publications

Panaxynol’s Pharmacokinetic Properties and Its Mechanism of Action in Treating Ulcerative Colitis, Hossam Sami Tashkandi
Theses and Dissertations

Design and Synthesis of Macrocyclic Peptide BRAF-WT Dimerization Inhibitors for the Treatment of Metastatic Melanoma, Chad Mulloy Beneker
Theses and Dissertations

Emergent Trends in the Chinese Counterfeit Pharmaceutical Supply Chain and Opportunities for Public-Private Reform, Mary Monk
Senior Theses

Potential Roles of Endoplasmic Reticulum Stress and Cellular Proteins Implicated in Diabesity, Sagir Mustapha, Mustapha Mohammed, Ahmad Khusairi Azemi, Ismaeel Yunusa, Aishatu Shehu, Lukman Mustapha, Yusuf Wada, Mubarak Hussaini Ahmad, Wan Amir Wan Ahmad, Aida Hanum Ghulam Rasool, Siti Safiah Mokhtar
Faculty Publications

Hearing Loss Prevalence and Years Lived With Disability, 1990–2019: Findings From the Global Burden of Disease Study 2019, Ismaeel Yunusa, Lydia M. Haile, Kaloyan Kamenov, Paul Svitil Briant, Aislyn U. Orji, Jaimie D. Steinmetz, Et. Al.
Faculty Publications

Public Opinion Regarding Government Response to COVID-19: Case Study of a Large Commercial City in Nigeria, Ismaeel Yunusa Ph.D., Sorochi Iloanusi, Osaro Mgbere, Nchebe-Jah Raymond Iloanusi, Anthony Idowu Ajayi, Ekere James Essien
Faculty Publications

Application of Standardized Antimicrobial Administration Ratio as a Motivational Tool Within a Multi-Hospital Healthcare System, Stephanie Shealy, Joseph Kohn, Emily Yongue, Casey Troficanto, P Brandon Bookstaver, Julie Ann Justo, Hana R. Winders, Sangita Dash, Majdi N. Al-Hasan
Faculty Publications

Less Common Bacterial, Fungal and Viral Infections: Review of Management in the Pregnant Patient, Alyssa P. Gould, Hana R. Winders, Kayla R. Stover, P Brandon Bookstaver, Brooke Griffin, Christopher M. Bland, Lea S. Eiland, Milena Murray
Faculty Publications

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs, Amanda C. Sharko, Chang-Uk Lim, Martina S.J. McDermott, Chuck Hennes, Kingsavanh P. Philavong, Tiffanie Aiken, Victor V. Tatarskiy, Igor Roninson Ph. D., Eugenia Broude
Faculty Publications

A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in 2019, Kayla R. Stover, Elias B. Chahine, David Cluck, Sarah Green, Daniel B. Chastain, Darrell Childress, Carmen Faulkner-Fennell, Katherine Lusardi, Edoabasi U. McGee, Michelle Turner, P Brandon Bookstaver, Christopher M. Bland
Faculty Publications

Early-Onset Colorectal Cancer in Mice, Qi Zhang
Theses and Dissertations

Empirical Fluoroquinolones Versus Broad-Spectrum Beta-Lactams for Gram-Negative Bloodstream Infections in the Absence of Antimicrobial Resistance Risk Factors, Majdi N. Al-Hasan, Alyssa P. Gould, Chelsea Drennan, Olivia Hill, Julie Ann Justo, Joseph Kohn, P Brandon Bookstaver
Faculty Publications

Redox-Sensitive Nanocomplex for Targeted Delivery of Melittin, Bei Cheng, Peisheng Xu
Faculty Publications

Function of GPR68 in Normal Hematopoiesis and Malignant Hematopoietic Diseases, Xiaofei He
Theses and Dissertations

The Association Between Phosphodiesterase-5 Inhibitors and Colorectal Cancer in a National Cohort of Patients, S. Scott Sutton, Joseph Magagnoli, Tammy H. Cummings, James W. Hardin
Faculty Publications

Prediction of Trimethoprim/Sulfamethoxazole Resistance in Community-Onset Urinary Tract Infections, Madeline DeMarsh, P Brandon Bookstaver, Caroline Gordon, Juanne Lim, Nicole Griffith, Nicole K. Bookstaver, Julie Ann Justo, Joseph Kohn, Majdi N. Al-Hasan
Faculty Publications

The Mbeya Antimicrobial Stewardship Team: Implementing Antimicrobial Stewardship at a Zonal-Level Hospital in Southern Tanzania, Jeffrey W. Hall, Jeannette Bouchard, P Brandon Bookstaver, Matthew S. Haldeman, Peter Kishimbo, Godlove Mbwanji, Issakwisa Mwakyula, Davance Mwasomola, Megan Seddon, Mark Shaffer, Stephanie C. Shealy, Anthony Nsojo
Faculty Publications

Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to Enterobacter, Serratia, and Citrobacter Species, Caroline Derrick, P. Brandon Bookstaver, Zhiqiang K. Lu, Christopher M. Bland, S. Travis King, Kayla R. Stover, Kathey Rumley, Shawn H. MacVane, Jenna Swindler, Scott Kincaid, Trisha Branan, David Cluck, Benjamin Britt, Kelly E. Pillinger, Bruce M. Jones, Virginia Fleming, V. Paul DiMondi, Sandy Estrada, Brad Crane, Brian Odle, Majdi N. Al-Hasan, Julie Ann Justo
Faculty Publications

PLK1 PBD Selective Inhibition as a Potential Cancer Therapy, Lauren E. Wilder
Senior Theses

Treatment With Protease Inhibitor and Development of Diabetes Among Medicare Beneficiaries With Human Immune Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS), Eric Ejike Chinaeke
Theses and Dissertations

Influenza Vaccination Coverage in Pediatric Patients with Inflammatory Bowel Disease, Kelly Brown
Senior Theses

Impact of Reappraisal of Fluoroquinolone Minimum Inhibitory Concentration Susceptibility Breakpoints in Gram-Negative Bloodstream Isolates, Stephanie C. Shealy, Matthew M. Brigmon, Julie Ann Justo, P Brandon Bookstaver, Joseph Kohn, Majdi N. Al-Hasan
Faculty Publications

Pharmacist-Driven Culture and Sexually Transmitted Infection Testing Follow-Up Program in the Emergency Department, Stephanie C. Shealy, Christine Alexander, Tina Grof Hardison, Joseph Magagnoli, Julie Ann Justo, Caroline Derrick, Joseph Kohn, Hana Rac Winders, Troy Privette, Majdi N. Al-Hasan, P. Brandon Bookstaver
Faculty Publications

Healthcare Practitioners’ Views of Social Media as an Educational Resource, Adam G. Pizzuti, Karan H. Patel, Erin K. McCreary, Emily Heil, Christopher M. Bland, Eric Chinaeke, Bryan L. Love, P Brandon Bookstaver
Faculty Publications

Online Availability of Fish Antibiotics and Documented Intent for Self-Medication, Weiwei Zhang, Austin Williams, Nicole Griffith, Jessica Gaskins, P Brandon Bookstaver
Faculty Publications

Evaluating Appropriateness and Diagnostic Stewardship Opportunities of Multiplex Polymerase Chain Reaction Gastrointestinal Testing Within a Hospital System, Melissa O'Neal, Hanna Murray, Sangita Dash, Majdi N. Al-Hasan, Julie Ann Justo, P Brandon Bookstaver
Faculty Publications

A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in 2018, Elias B. Chahine, Spencer H. Durham, Krutika N. Mediwala, Daniel B. Chastain, Timothy P. Gauthier, Brandon K. Hill, Bruce M. Jones, Jamie J. Kisgen, Ashley H. Marx, Kayla R. Stover, Marylee V. Worley, Christopher M. Bland, P Brandon Bookstaver
Faculty Publications

Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition, Mengqian Chen, Jing Li, Jiaxin Liang, Zanshé S. Thompson, Katie Kathrein, Eugenia Broude, Igor Roninson
Faculty Publications

Susceptibility to Metabolic Disease and Individual Variations in Unfolded Protein Response in Deer Mice (Peromyscus Maniculatus), Amanda Rose Havighorst
Theses and Dissertations

Analysis of HPV16 Variants in the Carolina Women’s Care Study and a Comparison of Gene Expression Profiles of Exfoliated Cervical Cells From Women Who Either Clear or Do Not Clear an HPV16 Infection, Erica Shirlene Green
Theses and Dissertations

Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay, Jng Li, Donald C. Porter, Eugenia Broude, Igor Roninson, Mengqian Chen
Faculty Publications

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting, Wesley D. Kufel, Julie Ann Justo, P. Brandon Bookstaver, Lisa M. Avery
Faculty Publications

Identifying Cancers for CDK8/19 Inhibitor Therapy, Igor Roninson, Balázs Győrffy, Zachary T. Mack, Alexander A. Shtil, Michael S. Shtutman, Mengqian Chen, Eugenia Broude
Faculty Publications

Penicillin Allergy Skin Testing in the Inpatient Setting, Julie Ann Justo, Wesley D. Kufel, Lisa Avery, P. Brandon Bookstaver
Faculty Publications

Direct Measurement of Performance: A New Era in Antimicrobial Stewardship, Majdi N. Al-Hasan, Hana Rac Winders, P. Brandon Bookstaver, Julie Ann Justo
Faculty Publications

Glia Responsivity in Nicotine Dependence, Adewale Oluwamuyiwa Adeluyi
Theses and Dissertations

Investigating the Neural Correlates of Nicotine Withdrawal Phenotypes in Mice: Involvement of CREB-dependent NRG3-ErbB4 Signaling in Mediating Anxiety-like Behavior, Miranda Fisher
Theses and Dissertations

Effects of Human Dopamine Transporter (DAT) Mutations and Novel Allosteric Modulatory Compounds in Disrupting HIV-1 Tat-DAT Protein Interaction, Pamela Marie P. Quizon
Theses and Dissertations

Torsades de Pointes and Qt Prolongation Associations With Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System, Chengwen Teng Pharm.D., Ph.D., Elizabeth A. Walter, Daryl Kevin S. Gaspar, Obiageri O. Obodozie-Ofoegbu, Christopher R. Frei
Faculty Publications

Comparison of Quetiapine Abuse and Misuse Reports to the FDA Adverse Event Reporting System With Other Second-Generation Antipsychotics, Kirk E. Evoy, Chengwen Teng Pharm.D., Ph.D., Victor G. Encarnacion, Brian Frescas, John Hakim, Stephen Saklad, Christopher R. Frei
Faculty Publications

Cellular Localization of RAD51D Mutant Proteins and the Application of Art to Increase Scientific Literacy in America, Claire L. Chabot
Senior Theses

Clostridium Difficile Infection Risk With Important Antibiotic Classes: An Analysis of the FDA Adverse Event Reporting System, Chengwen Teng Pharm.D., Ph.D., Kelly R. Reveles, Obiageri O. Obodozie-Ofoegbu, Christopher R. Frei
Faculty Publications

A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in 2017, Daniel B. Chastain, David B. Cluck, Kayla R. Stover, Katherine T. Lusardi, Ashley Marx, Sarah Green, Carmen Faulkner-Fennell, Michelle Turner, Elias B. Chahine, P Brandon Bookstaver, Christopher M. Bland
Faculty Publications

The Pharmabiotic for Phenylketonuria: Development of a Novel Therapeutic, Chloé Elizabeth LeBegue
Senior Theses

Utility of Combination Antimicrobial Therapy in Adults with Bloodstream Infections Due to Enterobacteriaceae and Non-Fermenting Gram-Negative Bacilli Based on in Vitro Analysis at Two Community Hospitals, Rachel Foster, Casey Troficanto, P. Brandon Bookstaver, Joseph Kohn, Julie Ann Justo, Majdi Al-Hasan
Faculty Publications

Rhabdomyolysis Associations With Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS), Chengwen Teng Pharm.D., Ph.D., Courtney Baus, James P. Wilson, Christopher R. Frei
Faculty Publications

Role of Transcription-Regulating Kinase CDK8 in Colon Cancer Metastasis, Jiaxin Liang, Mengqian Chen, Eugenia Broude, Igor Roninson
Faculty Publications

Bloodstream Infection Due to Piperacillin/Tazobactam Non-Susceptible, Cephalosporin Susceptible Escherichia Coli: A Missed Opportunity for DE-Escalation of Therapy, Leah Carlisle, Julie Ann Justo, Majdi N. Al-Hasan
Faculty Publications

Multidisciplinary Authorship Among Infectious Diseases Society of America Clinical Practice Guidelines: Examining the Contributions of Infectious Diseases Pharmacists, Lauren K. Freeman, Jasmine N. Lindsay, Sarah Elizabeth Davis, Brian F. Norman, April W. Thompkins, Vera P. Luther, Christopher A. Ohl, P Brandon Bookstaver
Faculty Publications

The Role of CDK8 in Metastatic Growth of Colon Cancer, Jiaxin Liang
Theses and Dissertations

Ubiquitin Receptor RPN13 Mediates the Inhibitory Interaction of Diphenyldihaloketones CLEFMA and EF24 With the 26S Proteasome, Geeta Rao, Gregory Nkepang, Jian Xu, Hooman Yari, Hailey Houson, Chengwen Teng Pharm.D., Ph.D., Vibhudutta Awasthi
Faculty Publications

Impact of Outpatient vs Inpatient ABSSSI Treatment on Outcomes: A Retrospective Observational Analysis of Medical Charts Across US Emergency Departments, P Brandon Bookstaver, Timothy C. Jenkins, Edward Stenehjem, Shira Doron, Jack Brown, Shannon H. Goldwater, Carlos Lopes, Angela Haynes, Chuka Udeze, Yifan Mo, Patrick Gillard, Yan Liu, Katelyn Keyloun
Faculty Publications

Evaluation of Pharmacy Students’ Tendency to Self-Medicate, Rebekah Lee Crandall, Danielle O'Neal
Senior Theses

Kv7 Channels Of The Urinary Bladder Smooth Muscle: Functional Roles And Therapeutic Potential, Aaron Provence
Theses and Dissertations

Mechanisms Of RAD51D-Dependent Repair Of DNA And Telomere Damage Induced By Interstrand Crosslinking Agents And Thiopurines, Nicole M. Reilly
Theses and Dissertations

The Effects Of Stand-Alone Prescription Drug Plans On Health Care Utilizations, Expenditures And Medication Adherence Among Elderly Medicare Beneficiaries, Jing Yuan
Theses and Dissertations

Mechanism Of Action Of American Ginseng And Its Components In The Treatment Of Ulcerative Colitis, Anusha Chaparala
Theses and Dissertations

Clostridium tertium Peritonitis and Concurrent Bacteremia in a Patient With a History of Alcoholic Cirrhosis, S. Scott Sutton, Mark Jumper, Ansal Shah, Babatunde Edun
Faculty Publications

Application of Fluoroquinolone Resistance Score in Management of Complicated Urinary Tract Infections, Ansal Shah, Julie Ann Justo, P Brandon Bookstaver, Joseph Kohn, Helmut Albrecht, Majdi N. Al-Hasan
Faculty Publications

Inhibition of CDK8 Mediator Kinase Suppresses Estrogen Dependent Transcription and the Growth of Estrogen Receptor Positive Breast Cancer, Martina S. McDermott, Alexander A. Chumanevich, Chang-Uk Lim, Jiaxin Liang, Mengqian Chen, Serena Altilia, David Oliver, James M. Rae, Michael Shtutman, Hippokratis Kiaris, Balázs Győrffy, Igor Roninson, Eugenia Broude
Faculty Publications

Impact of Medicare Reimbursement Policy Change on the Utilization, Risks, and Costs Associated with Erythropoiesis-Stimulating Agents in Cancer Patients with Chemotherapy-Induced Anemia, Minghui Li
Theses and Dissertations

Ertapenem-Induced Encephalopathy in a Patient With Normal Renal Function, S. Scott Sutton, Mark Jumper, Michael D. Wyatt
Faculty Publications

Impact Of Prenatal Exposure To Antidepressants On Adverse Birth Outcomes, Sudeepti Pahuja
Theses and Dissertations

Management of Viral Central Nervous System Infections: A Primer for Clinicians, P Brandon Bookstaver, Phillip L. Mohorn, Ansal Shah, Lauren D. Tesh, April M. Quidley, Ravish Kothari, Christopher M. Bland, Sharon Weissman
Faculty Publications

Chlor-Amidine, A Novel PAD Inhibitor, As An Effective Drug For The Treatment Of Ulcerative Colitis And Prevention Of Colorectal Cancer, Erin Witalison
Theses and Dissertations

The Effect Of Depression And Antidepressants On Cost, Survival And Adherence To Hormone Therapy In Breast Cancer, Virginia Noxon
Theses and Dissertations

Prediction of Fluoroquinolone Resistance in Gram-Negative Bacteria Causing Bloodstream Infections, Seejil Dan, Ansal Shah, Julie Ann Justo, P Brandon Bookstaver, Joseph Kohn, Helmut Albrecht, Majdi N. Al-Hasan
Faculty Publications

Stimuli Responsive Nanoparticle for Cancer Targeted Therapy, Huacheng He
Theses and Dissertations

Multifunctional Nanocarriers for Cancer Therapy, Bei Cheng
Theses and Dissertations

High-Throughput Sequencing-Based Approaches for the Identification and Development of Molecular Targets for Cancer Therapy, David Joel Oliver
Theses and Dissertations

Selectivity Targeting Polo-Like Kinase 1 (PLK1) Using Novel Inhibitors of the Polo-Box Domain, Merissa Lynnea Baxter
Theses and Dissertations

Identification of Novel Genes That Regulate Androgen Receptor Signaling and Growth of Androgen-Deprived Prostate Cancer Cells, Elina Levina, Hao Ji, Mengqiang Chen, Mirza Baig, David Oliver, Patrice Ohouo, Chang-Uk Lim, Garry Schools, Steven Carmack, Ye Ding, Eugenia Broude, Igor Roninson, Ralph Buttyan, Michael Shtutman
Faculty Publications

Stratification of the Impact of Inappropriate Empirical Antimicrobial Therapy for Gram-Negative Bloodstream Infections by Predicted Prognosis, Sarah E. Cain, Joseph Kohn, P. Brandon Bookstaver, Helmut Albrecht, Majdi N. Al-Hasan
Faculty Publications

Molecular Mechanisms Underlying Environmental Enrichment-Induced Neuroprotection in Vulnerability to Nicotine Addiction, Adrian Michael Gomez
Theses and Dissertations

Design and Development of a Novel Class of Cell Cycle CDK Inhibitors Targeting the Cyclin Binding Groove Utilizing the Replace Strategy, Padmavathy Nandha Premnath
Theses and Dissertations

Musculoskeletal Safety Outcomes of Patients Receiving Daptomycin With HMG-COA Reductase Inhibitors, Christopher M. Bland, P Brandon Bookstaver, Z Kevin Lu, Brianne L. Dunn, Kathey Fulton Rumley
Faculty Publications

INVESTIGATION OF THE RESPONSE AND REPAIR OF REPLICATION, Kathryn Brady
Theses and Dissertations

EFFECTS OF HIV-1 TAT PROTEIN ON STRUCTURE, FUNCTION AND TRAFFICKING OF THE DOPAMINE TRANSPORTER, Narasimha Murty Midde
Theses and Dissertations

SIX1 OVEREXPRESSION PROMOTES EPITHELIAL– MESENCHYMAL TRANSITION AND MALIGNANT PROGRESSION IN MODELS OF CERVICAL AND COLON CANCER, Hanwen Xu
Theses and Dissertations

Antibiotic Lock Therapy: Review of Technique and Logistical Challenges, Julie Ann Justo, P Brandon Bookstaver
Faculty Publications

Role of Micro RNA 148/152 Family in Cancer Progression, Anusha Chaparala
Theses and Dissertations

A Novel Approach to the Design of Selective Inhibitors for Cell Cycle Cyclin Dependent Kinases, Tracy Perkins
Theses and Dissertations

Effects of DNA Damage and CDK Inhibitors on the Nucleoli, Vineet Garg
Theses and Dissertations

Bioassay Guided Fractionation of American Ginseng. A Hexane Fraction of American Ginseng Suppresses Colitis and Associated Colon Cancer. Mechanism of Action., DEEPAK POUDYAL
Theses and Dissertations

K+ Channels and Beta3 Adrenergic Receptors as New Pharmacological Targets for Overactive Bladder Treatment, Serge Amani Yao Afeli
Theses and Dissertations

Nonionic Block Copolymers Assemble on the Surface of Protein Bionanoparticle, Zhi Liu, Jingxia Gu, Man Wu, Shidong Jiang, Dayong Wu, Qian Wang, Zhongwei Niu, Yong Huang
Faculty Publications

Multivalent Ligand Displayed on Plant Virus Induces Rapid Onset of Bone Differentiation, L. Andrew Lee, Sevan M. Muhammad, Quyen L. Nguyen, Pongkwan Sitasuwan, Gary C. Horvath, Qian Wang
Faculty Publications

Role of Raltegravir in HIV-1 Management, Kristina E. Rokas, P Brandon Bookstaver, Caitlin L. Shamroe, S Scott Sutton, Vanessa E. Millisor, Jacquelyn E. Bryant, Sharon B. Weissman
Faculty Publications

Reactive Oxygen Species and Mitochondrial Sensitivity to Oxidative Stress Determine Induction of Cancer Cell Death by p21, Ionica Masgras, Samantha Carrera, Petra J. de Verdier, Paul Brennan, Aneela Majid, Wan Makhtar, Eugene Tulchinsky, George D. Jones, Igor Roninson, Salvador Macip
Faculty Publications

TP53 Codon 72 Polymorphism Affects Accumulation of mtDNA Damage in Human Cells, Serena Altilia, Aurelia Santoro, Davide Malagoli, Catia Lanzarini, Josué Adolfo Ballesteros Álvarez, Gianluca Galazzo, Donald Carl Porter, Paolina Crocco, Giuseppina Rose, Giuseppe Passarino, Igor Roninson, Claudio Franceschi, Stefano Salvioli
Faculty Publications

Design of Non-ATP Competitive and Cell Cycle Specific CDK Inhibitors Targeting Cyclin Binding Groove, Shu Liu
Theses and Dissertations

Relationship Between Vancomycin Trough Concentrations and Nephrotoxicity: A Prospective Multicenter Trial, John A. Bosso, Jean Nappi, Celeste Rudisill, Marlea Wellein, P Brandon Bookstaver, Jenna Swindler, Patrick D. Mauldin
Faculty Publications

Topiramate: Safety and Efficacy of Its Use in the Prevention and Treatment of Migraine, Ginger C. Minton, April D. Miller, P Brandon Bookstaver, Bryan L. Love
Faculty Publications

Model-Based Measures Of Interrater Agreement, Jie Gao
Theses and Dissertations

Folate Deficiency and Its Effect On Dna Repair, Virginia Noxon
Theses and Dissertations

DNA Damage and Cell Death Mediated by Thymidylate Synthase Inhibitors: Role of UNG and SMUG1 DNA Glycosylase, Pratik K. Nagaria
Theses and Dissertations

Development of Non-Atp Competitive, Plk1-Selective Inhibitors, Kara Michelle Estes
Theses and Dissertations

Computational and Pharmacological Approaches to Design Novel Allosteric Thymidylate Synthase Inhibitors, Jayanthi Repalli
Theses and Dissertations

Regulation of Rad51D In Homologous Recombination Dna Repair by Alternative Splicing and Ubiquitin Modification, Brian David Yard
Theses and Dissertations

Intravenous Ibuprofen: The First Injectable Product for the Treatment of Pain and Fever, P Brandon Bookstaver, April D. Miller, Celeste N. Rudisill, Leann B. Norris
Faculty Publications

Chemical Modification of M13 Bacteriophage and Its Application in Cancer Cell Imaging, Kai Li, Yi Chen, Siqi Li, Huong Giang Nguyen, Zhongwei Niu, Shaojin You, Charlene M. Mello, Xiaobing Lu, Qian Wang
Faculty Publications

Virus-Triggered Ubiquitination of TRAF3/6 by cIAP1/2 Is Essential for Induction of Interferon- &Beta (IFN-&Beta) and Cellular Antiviral Response, Ai-Ping Mao, Shu Li, Bo Zhong, Ying Li, Jie Yan, Qi Li, Chengwen Teng Pharm.D.. Ph.D, Hong-Bing Shu
Faculty Publications

Clinical Outcomes of Antimicrobial Lock Solutions Used in a Treatment Modality: A Retrospective Case Series Analysis, P Brandon Bookstaver, Katherine R. Gerrald, Robert R. Moran
Faculty Publications

Interactions between Folate Deficiency and β-Nicotinamide Adenine Dinucleotide Deficiency and Conformational Study of Thymidylate Synthase and its Physiological Relevance, Beibei Luo
Theses and Dissertations

Differences in Hospital Glycemic Control and Insulin Requirements in Patients Recovering From Critical Illness and Those Without Prior Critical Illness, April D. Miller, Leslie M. Phillips, Richard M. Schulz, P Brandon Bookstaver, Celeste N. Rudisill
Faculty Publications

Homology-Directed Repair of Dna Lesions Generated by the Mismatch Repair Dependent Processing of Cytotoxic Guanine Adducts, Preeti Rajesh
Theses and Dissertations

Identification of Single Nucleotide Polymorphisms in the P21 (CDKN1A) Gene and Correlations With Longevity in the Italian Population, Silvia Gravina, Francesco Lescai, Gregory Hurteau, Graham J. Brock, Anna Saramaki, Stefano Salvioli, Claudio Franceschi, Igor Roninson
Faculty Publications

Effects of the AMPA Receptor Modulator S 18986 on Measures of Cognition and Oxidative Stress in Aged Rats, Sandra J. Kelly, K. Bernard, C. Muñoz, R. C. Lawrence, J. Thacker, Claudia A. Grillo, Gerardo G. Piroli, Lawrence P. Reagan
Faculty Publications

Molecular Mechanisms of American Ginseng For the Prevention and Treatment of Colitis and Colon Cancer Associated With Colitis, Yu Jin
Theses and Dissertations

A Structural Interpretation of the Effect of GC-Content on Efficiency of RNA Interference, Chi Yu Chan, C Steven Carmack, Dang D. Long, Anil Maliyekkel, Yu Shao, Igor Roninson, Ye Ding
Faculty Publications

Repression of the Sumo-Specific Protease SENP1 Induces P53-Dependent Premature Senescence in Normal Human Fibroblasts, Kristin E. Yates, Gregory A. Korbel, Michael Shtutman, Igor Roninson, Daniel DiMaio
Faculty Publications

Developmental Changes in Alcohol Pharmacokinetics in Rats, Sandra J. Kelly, D. J. Bonthius, J. R. West
Faculty Publications