A Case-Control Study of the Association Between Sialolithiasis and Osteoporosis
Document Type
Article
Abstract
OBJECTIVE: The purpose of this study was to evaluate the association between osteoporosis and salivary gland stone using a population-based claims database. DESIGN: A case-control design. SETTING: Taiwan. PARTICIPANTS: We retrieved the sample for this case-control study from the Taiwan "Longitudinal Health Insurance Database 2005." All 557 patients aged 40 years or older with a diagnosis of sialolithiasis were cases, and 1671 matched controls (without sialolithiasis) were selected. SUBJECTS AND METHODS: We used the chi-square test to explore differences between cases and controls on socio-demographic characteristics. Furthermore, conditional logistic regressions were used to examine the association of sialolithiasis with previously diagnosed osteoporosis. RESULTS: Of 2228 sampled patients, 171 (7.68%) had ever been previously diagnosed with osteoporosis; 58 (10.41%) among cases and 113 (6.76%) among controls (P = 0.005). Conditional logistic regression analysis found that the odds ratio (OR) of prior osteoporosis for cases was 1.79 (95% confidence interval [CI]: 1.24-2.59, P = 0.002) relative to controls after adjusting for urbanisation and the selected medical co-morbidities. Furthermore, we found that among patients aged ≥65 years, the adjusted OR of prior osteoporosis for cases was 1.89 (95% CI = 1.02-3.51). No significant relationship was observed among patients aged investigation, the results call for more awareness of the possible concurrence of osteoporosis among physicians and patients with salivary gland stones.
Digital Object Identifier (DOI)
Publication Info
Published in Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, Volume 44, Issue 3, 2019, pages 343-348.
APA Citation
Hung, S., Sudha Xirasagar, Cheng, Y., & Lin, H. (2019). A case‐control study of the association between sialolithiasis and osteoporosis. Clinical Otolaryngology, 44(3), 343–348.https://doi.org/10.1111/coa.13310
Rights
© 2019 John Wiley & Sons Ltd