Theses/Dissertations from 2023
Drug Repurposing: New Mechanisms and Applications of Existing Compounds, Biyun Celia Cui
CDK8 AND CDK19 Mediator Kinases as Novel Targets in Advanced Prostate Cancer, Jing Li
Targeting of Mediator Kinases for Cancer Therapy and Resistance Prevention, Zachary Thomas Mack
PD-L1 Nano-Eraser: A Novel Intracellular PD-L1 Degradation Approach and Its Application in Cancer and Alzheimer’s Disease Therapy, Mingming Wang
Prevalence, Disparities, and Health Outcomes in Patients With Alzheimer’s Disease, Dementia, and Mild Cognitive Impairment, Xiaomo Xiong
Theses/Dissertations from 2022
Discovery and Mechanistic Study of Novel PBD-Targeted Inhibitors of PLK1 for Prostate Cancer Treatment, Danda Pani Chapagai
Mediator Kinase Inhibitors for Breast Cancer Therapy, Xiaokai Ding
Peromyscus Maniculatus Bairdii and Peromyscus Maniculatus Sonoriensis Polymorphisms, Matthew Dixon Lucius
Changes in the Regulation of the Unfolded Protein Response During Aging in Peromyscus, Elham Soltanmohammadi
Development of Peptidomimetic Inhibitors Targeting the Polo Box Domain of PLK1 as Potential Cancer Therapeutics, Jessy Mariam Stafford
Theses/Dissertations from 2021
The Association of Antidepressants Use with Healthcare Utilization, Patient-Reported Outcomes, and Alzheimer's Disease and Related Dementias (ADRD) Among Medicare Beneficiaries with Depression, Abdulrahman Abdullah A Alnijadi
Sex Differences and Neuroimmune Effects of Microglial Response in the Mesolimbic Reward Pathway in Nicotine Substance Use Disorder, Erin Leigh Anderson
Panaxynol’s Pharmacokinetic Properties and Its Mechanism of Action in Treating Ulcerative Colitis, Hossam Sami Tashkandi
The Development of Novel CDK8 and CDK19 Inhibitors and Degraders as Potential Anti-cancer Agents, Li Zhang
Variations in ER Stress and Unfolded Protein Response Predict Disease Susceptibility, Youwen Zhang
Theses/Dissertations from 2019
Glia Responsivity in Nicotine Dependence, Adewale Oluwamuyiwa Adeluyi
Susceptibility to Metabolic Disease and Individual Variations in Unfolded Protein Response in Deer Mice (Peromyscus Maniculatus), Amanda Rose Havighorst
Effects of Human Dopamine Transporter (DAT) Mutations and Novel Allosteric Modulatory Compounds in Disrupting HIV-1 Tat-DAT Protein Interaction, Pamela Marie P. Quizon
Theses/Dissertations from 2018
Kv7 Channels Of The Urinary Bladder Smooth Muscle: Functional Roles And Therapeutic Potential, Aaron Provence
Theses/Dissertations from 2017
Impact Of Prenatal Exposure To Antidepressants On Adverse Birth Outcomes, Sudeepti Pahuja
Theses/Dissertations from 2016
Selectivity Targeting Polo-Like Kinase 1 (PLK1) Using Novel Inhibitors of the Polo-Box Domain, Merissa Lynnea Baxter
Multifunctional Nanocarriers for Cancer Therapy, Bei Cheng
Stimuli Responsive Nanoparticle for Cancer Targeted Therapy, Huacheng He
The Effect Of Depression And Antidepressants On Cost, Survival And Adherence To Hormone Therapy In Breast Cancer, Virginia Noxon
High-Throughput Sequencing-Based Approaches for the Identification and Development of Molecular Targets for Cancer Therapy, David Joel Oliver
Chlor-Amidine, A Novel PAD Inhibitor, As An Effective Drug For The Treatment Of Ulcerative Colitis And Prevention Of Colorectal Cancer, Erin Witalison
Theses/Dissertations from 2015
Molecular Mechanisms Underlying Environmental Enrichment-Induced Neuroprotection in Vulnerability to Nicotine Addiction, Adrian Michael Gomez
Theses/Dissertations from 2014
Role of Micro RNA 148/152 Family in Cancer Progression, Anusha Chaparala
Design and Development of a Novel Class of Cell Cycle CDK Inhibitors Targeting the Cyclin Binding Groove Utilizing the Replace Strategy, Padmavathy Nandha Premnath
Theses/Dissertations from 2013
K+ Channels and Beta3 Adrenergic Receptors as New Pharmacological Targets for Overactive Bladder Treatment, Serge Amani Yao Afeli
Effects of DNA Damage and CDK Inhibitors on the Nucleoli, Vineet Garg
A Novel Approach to the Design of Selective Inhibitors for Cell Cycle Cyclin Dependent Kinases, Tracy Perkins
Theses/Dissertations from 2012
Design of Non-ATP Competitive and Cell Cycle Specific CDK Inhibitors Targeting Cyclin Binding Groove, Shu Liu
Ca2+-Activated K+ Channels in Urinary Bladder Smooth Muscle: Functional Role and Potential as Therapeutic Targets for Overactive Bladder, Rupal Pandey Soder
Theses/Dissertations from 2011
Development of Non-Atp Competitive, Plk1-Selective Inhibitors, Kara Michelle Estes
Model-Based Measures Of Interrater Agreement, Jie Gao
DNA Damage and Cell Death Mediated by Thymidylate Synthase Inhibitors: Role of UNG and SMUG1 DNA Glycosylase, Pratik K. Nagaria
Folate Deficiency and Its Effect On Dna Repair, Virginia Noxon
Computational and Pharmacological Approaches to Design Novel Allosteric Thymidylate Synthase Inhibitors, Jayanthi Repalli
Regulation of Rad51D In Homologous Recombination Dna Repair by Alternative Splicing and Ubiquitin Modification, Brian David Yard
Theses/Dissertations from 2010
Homology-Directed Repair of Dna Lesions Generated by the Mismatch Repair Dependent Processing of Cytotoxic Guanine Adducts, Preeti Rajesh